Longevinex® Proven Better Than Resveratrol or Calorie Restriction (866)405-4000

Longevinex® rapidly activates white blood cells in humans with sluggish immune response. Longevinex® rapidly resolves platelet clumping.

October 21, 2009

Commentary on Roger Cohen's Op-Ed piece in The New York Times entitled "The Meaning of Life." - by Bill Sardi

July 16, 2009

Longevinex Advantage® -- Resveratrol Pills May Help You Live Longer, But Will You Look Any Younger? New Longevinex Advantage® Designed For Americans Who Want To Live Longer And Look Younger.

May 18, 2009

Brain Aging Begins In The 3rd Decade Of Life; Suggests Earlier Intervention With Iron and Calcium Chelators (key-lay-torz) Like Resveratrol, Quercetin and Bran Factors

March 15, 2009

Longevinex®

1. Longevinex® Rapidly Activates White Blood Cells In Humans With Sluggish Immune Response
2. Biological effects of red wine molecules by far exceed those of resveratrol
3. 2008 End-Of-Year Report on Advances in Anti-Aging
4. Longevinex®-like Nutriceuticals May Supersede Biotech Drugs
5. Secret of Profound Mental Acuity With Longevinex® Revealed
6. Researchers Link Progressive Accumulation of Iron With Age-Related Muscle Loss
7. Synopsis of Rapidly Changing Longevity Science
8. The All New 3rd Generation Longevinex
9. Longevinex® Affects 9-Fold More Longevity Genes
10. Why Vitamin D?
11. Longevinex® Quick Facts Sheet
12. Calorie Restriction and Longevity Timeline
13. 2007 In Review of an Anti-Aging Pill
14. The Quest for an Anti-Aging Pill 2005

Dosage

15. Dose determines whether resveratrol produces longevity or kills cancer
16. Longevity Seekers Advised To Consume Modest Doses of Red Wine Molecules
17. Resveratrol Sends Survival or Death Signals, Depending Upon Dosage
18. Plain Mega-Dose Resveratrol Fails To Mimic Calorie Restriction
19. Resveratrol Dosage Effects Unraveled
20. Harvard Researcher Changes Course, Opts To Promote Lower-Dose Resveratrol
21. The High-Dose Resveratrol Club and Topsy-Turvy Longevity Science
22. How Did We Get to the Idea of Taking 7000mg/day of Resveratrol?
23. Why Didn’t The Laboratory Mice Live Longer On Resveratrol?
24. Follow-Up Resveratrol Mouse Study
25. Resveratrol: High-Dose Not Required
26. Resveratrol Dosage Conversion from Animals to Humans

Sirtuin 1 Gene

27. Down-regulation of Sirtuin1 Gene Inhibits Human Prostate Cancer Cell Growth
28. Is the activation of the Sirtuin1 gene by resveratrol good or bad?
29. Researchers Call For Major Shift In Research
30. Recent Studies Continue To Show Sirtuin1 Gne Activation To Be Deleterious
31. Report Identifies Life-Prolonging Technologies As Potentially Disrupting
32. Sirtuin Gene Update

Bioavailability

33. Micronized Resveratrol Matrix
34. Resveratrol Bio-Availability

Encapsulation

35. Exclusive Micro-Encapsulation
36. Encapsulation Requirements
37. Preserves Trans-Resveratrol 6x Better

About Resveratrol

38. Brain Aging Begins In The 3rd Decade Of Life
39. Antioxidant power of red wine polyphenols
40. Resveratrol Eradicates Brain Plaque
41. Inflamm-aging How to control TNF-factor
42. Quercetin not resveratrol, inhibits enzymes known to cause cancer
43. IP6 Rice Brand Extract Effects
44. Raise Vitamin D Levels, Live Longer
45. When Red Meat Meets Red Wine
46. Overmineralization Theory of AgingFlash
47. Resveratrol The Real Story
48. Is Resveratrol A Stable Molecule
49. Resveratrol Influences Gene Switching
50. Media Misdirects Wine vs. Wine Pills
51. Resveratrol Prolongs Life of Lab Mice
52. Resveratrol Prolongs Lifespan

Consumer Alerts

53. Commentary on Roger Cohen's Op-Ed piece in The New York Times
54. Plethora Quick-Buck Artists Selling “Free” Resveratrol Pills That Trap Consumers
55. E-mail Regarding Competition Comparisons
56. Biotivia FDA Consumer Alert
57. Revatrol Consumer Alert

60 Minutes Blunder: News Re port on Resveratrol Overlooks Longevinex® Which Activates More Longevity Genes than Resveratrol Red Wine Molecule or Calorie Restricted Diet

January 30, 2009

Scam ads for resveratrol. Consumers May Soon See Fewer Scam Ads Google banning advertisers, not just ads, from its ad network

consumeraffairs.com
November 25, 2009

8-Minute Film Documentary Explores Why Humans Age

To play click arrow above.

Why Humans Age is the title of an 8-minute documentary film narrated by Bill Sardi, co-founder and formulator of Longevinex® (long-jev-in-ex), a nutriceutical product designed to promote healthy aging.

The film presents the "overmineralization" theory of aging -- that humans begin to age biologically only after full childhood growth is achieved.

Longevinex® - the ONLY resveratrol-based nutriceutical to have undergone rigorous independent ANIMAL and HUMAN testing as evidenced in published studies
Animal studies	Human Studies
Year: 2008 Study group: laboratory mice, heart and brain tissue Result: Longevinex significantly altered 9-fold more genes (1711) than plain resveratrol (225) and calorie restriction (198) at a resveratrol dose 17-320 times lower than prior studies (100 mg human equivalent) Conducted by: Independent lab, published in Experimental Gerontology Sept 2008	Year: 2007 Study group: endurance athletes Result: significantly reduced measures of oxidation and inflammation Conducted by: Appalachian State Univ. Presented at: Annual Meeting of the American College of Sports Medicine, Southeast Chapter in February, 2008
Year: 2010 Study group: laboratory mice Result: Longevinex® tested for ability to limit damage from a heart attack. Conducted by: Dipak Das PhD, University of Connecticut Published results scheduled for early 2010	Year: 2009 Study group: adults with sticky blood platelets and/or sluggish white blood cells Result: 1 Longevinex® capsule rapidly reduced sticky blood platelets, activated white blood cells Conducted by: Nutriscreen
	Year: 2009 Study group: elderly male, poor night vision Result: Longevinex® produced visual improvement correlated with disappearance of cellular debris (lipofuscin) at the back of the eye; anti-aging effect Conducted by: Stuart Richer OD, PhD, published in Optometry, Dec. 2009
	Year: 2010 Study group: diabetic adults Result: will publish results examining blood sugar and other measurable parameters involving diabetics Conducted at: Kansai Medical University, Osaka, Japan Publication scheduled for 2010

Prescription Drug or Dietary Supplement? HOW DOES LONGEVINEX® COMPARE TO A $720 MILLION RESVERATROL DRUG
Product	SRT501 Experimental Drug	Longevinex®
Manufacturer	Sirtris Pharmaceuticals (GlaxoSmithKline)	Resveratrol Partners LLC
Regulatory Status	Prescription drug	Dietary Supplement
Intended use	Diabetes	Health & Longevity
Dosage of resveratrol per capsule	250 mg	100 mg
Synergistic molecules	Unknown	150 mg quercetin, rice bran, vitamin D3, ferulic acid
Molecular sizing	Micronized	Micronized
Emulsification	Yes	Yes
Stabilization	Claimed – nondescript; sealed capsule	Microencapsulation
Gene activation	Sirtuin 1 gene target	Activates 9 times more genes than plain resveratrol (Resveratrol 198 genes, Longevinex 1711 genes) Mouse study Experimental Gerontology August 2008

Signs & symptoms
of anemia and iron/copper overload
anemia		healthy zone		iron/copper overload
weakened immunity fatigue, dizziness, need naps poor mental concentration cold fingers/ toes crave ice chips crave acidic foods (tomatoes) leg cramps in bed insomnia shortness of breath headache underweight itching/hives heart palpitations, rapid heart beat optic nerve swelling (papilledema)		iron storage (ferritin) 20-50 hemoglobin 10-12		infection fatigue elevated liver enzymes inflammation joint problems gallstones increased hunger/overweight elevated insulin, blood sugar impotence skin bronzing heart problems sleep problems

PRODUCT COMPARISON

	PLAIN RESVERATROL BRANDS (Examples: Biotivia, Revatrol, Life Extension, Mega Resveratrol	LONGEVINEX® RESVERATROL MATRIX
Resveratrol dosage needed to mimic calorie restriction effect; 70 kg (160 lb) adult PLoS ONE. June 4, 2008	343 MG	100 MG*
Genomic effect (rodents) Experimental Gerontology 8/2008	225 GENES	1711 GENES
Activates FOXO1 longevity gene Experimental Gerontology 8/2008	NO	YES
Proven in human study	NO	YES**
Resveratrol preserved by microencapsulation or other technology	NO	YES
Immediate bio-availability enhanced	NO	YES
Absorption maximized by micronization	NO	YES
POTENTIAL SIDE EFFECTS Excessive dosage (increases potential for side effects; anemia, Achilles heel tendonitis, collagen breakdown)	YES	NO
Mineral chelation	CHELATES COPPER ONLY	CHELATES IRON, COPPER, CADMIUM, LEAD, MERCURY, CALCIUM
As employed with other natural mineral-chelating molecules * Significantly reduced oxidation and inflammation in endurance athletes- independent study

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.